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Figures Abstract The heavy metals (HMs) lead and cadmium are persistent environmental pollutants capable of inducing ill-health in exposed individuals

Discussion Complement and complement receptors are becoming recognized as potential targets for molecular anticancer therapy [40]

In addition to antioxidation and electron donation, GSH is also required for maintaining homeostasis in animals, such as detoxification, by forming conjugates with toxicants and suppressing apoptosis [8,9]

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In vitro experiments further confirmed that FGF21 protected HT22 cells from OGD/R-induced oxidative stress and ferroptosis, thereby attenuating neuronal injury (Zhao et al., 2025c)