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It is now well established that the unexpected beneficial effects of O 3 in biological tissues are related to its ability to stimulate the intracellular signaling and metabolism, to boost the tissue antioxidant and anti-inflammatory activities and to potentiate the immunological response

DC activation and maturation is a highly coordinated response associated with phenotypic and morphologic changes, which enable functional specialization for mounting protective immunity or tolerance to self-antigens 2

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[DOI] [PMC free article] [PubMed] [Google Scholar] 71.Noureddin M., Mato J.M., Lu S.C

Total prevention of the development of in vitro tolerance to organic nitrates

N., Turski, C
