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One drawback of these structures is that their uptake occurs via endocytosis, meaning that a sufficient quantity must escape the endosome if therapeutic targets are in the cytosol 89

With developments in novel skin permeation enhancing methods such as microneedles and laser, copper compounds can potentially be used on skin for cosmeceutical or medicinal purposes 5,11,12

J Ethnopharmacol 321:117438 Jeengar MK, Thummuri D, Magnusson M, Naidu VGM, Uppugunduri S (2017) Uridine ameliorates dextran sulfate sodium (DSS)-induced colitis in mice

Patients with a history of cancer, or those with elevated cancer risk, should approach peptide therapy with particular caution and only under close medical supervision

Rafael Franco is Editor-in-Chief of Exploration of Neuroprotective Therapy

Academic Press, pp 149164