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Pemetrexed administered intraperitoneally at doses of 0.1 mg/kg/day to male mice (approximately 0.0006 times the recommended human dose based on BSA) resulted in reduced fertility, hypospermia, and testicular atrophy

In experimental studies, AOD-9604 has been observed to stimulate fat oxidation , increase energy expenditure , and reduce adipose tissue accumulation through activation of beta-adrenergic lipolytic pathways

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Monotherapy Results of studies with either single-agent isatuximab after daratumumab or daratumumab after isatuximab have provided evidence of limited efficacy for anti-CD38 antibody monotherapy in RRMM

The institution operates under the principles of the Seventh-day Adventist organization, emphasizing a holistic approach to health care that integrates education and research

A mitochondrial UPR-mediated metabolic checkpoint regulates hematopoietic stem cell aging