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Significance of Macrophage Lipoprotein Receptors The significance of the numerous receptors on the surface of macrophages that specifically bind oxLDL is that the consequences are an enhanced intravascular inflammatory state

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Rose-John S, Winthrop K, Calabrese L.The role of IL-6 in host defence against infections: immunobiology and clinical implications.Nat Rev Rheumatol

MIA inflammatory mouse models have been developed, which demonstrate autism-like behavior and were found to have elevation of the pro-inflammatory signal interleukin-6 (IL-6) with resultant fetal neuronal death, inhibition of neurogenesis, and impaired neuronal migration [4]