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Description
NNMT consumes S-adenosylmethionine (SAM) and methylates nicotinamide, depleting cellular methyl pools and downstream NAD+ precursors
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Explore 5-Amino-1MQ, a compound researched for its modulation of NNMT activity and its role in energy balance, metabolism, and insulin sensitivity.
5-Amino-1MQ emerged from medicinal-chemistry programmes screening for selective NNMT inhibitors
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Simultaneously, the preservation of SAM levels maintains cellular methylation capacity for essential epigenetic modifications and protein functions
