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It creates an easy-to-calculate concentration of 5mg per mL, which simplifies dosing and minimizes the chance of mathematical errors
Similar to its impact on endothelial cells, HDL also suppresses adhesion molecule expression in monocytes, which inhibits monocyte adhesion and migration to atherosclerotic lesions (814)

doi: 10.1016/s0014-2999(02)02730-9

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The TCAs were largely replaced by SSRIs from 1990s with the hope that SSRIs would be more effective and safer than TCAs [104]
