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Research published in endocrinology journals notes that untreated or uncontrolled hyperthyroidism can worsen GLP-1 side effects including nausea and cardiovascular stress

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Schuettauf F, Naskar R, Vorwerk CK, Zurakowski D

Similarly, it has specific usage requirements which must be considered and followed

Use a broad-spectrum sunscreen SPF 50 or higher every morning

Apply a small amount of the soap to a discreet area and monitor for any adverse reactions over 24 hours