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Quisinostat mitigates renal fibrosis in the RTECs of the UUO-induced renal fibrosis mouse model and Ang II-treated HK-2 cells

These early results reflect reduced inflammatory burden and improved gut barrier integrity rather than dramatic toxin elimination

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When the equilibrium is directed towards fission, mitochondria are fragmented, respiration-incompetent and tend to lose mitochondrial DNA

As a result, studies can compare outcomes more clearly across phases while maintaining steady conditions
