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Description
It has been demonstrated that tumors that arise from cells with highly NAPRT expression will rely on NAD + de novo synthesis for survival

doi: 10.1038/s41591-020-0926-0 224 JohnsonDBNixonMJWangYWangDYCastellanosEEstradaMVet al

Additionally, there are limited treatments for non-motor symptoms, which can be significantly debilitating

Ou Y, Wang SJ, Jiang L, Zheng B, Gu W

Clin Chim Acta 510:442449

doi: 10.3390/ijms22157931
