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This therapy requires careful medical supervision and monitoring of kidney function and electrolyte levels

NRF2 plays a critical role in this process by upregulating the expression of genes involved in the synthesis of -GC, thereby increasing the overall production of GSH [34]

These data indicate that decrements in IGF-I and IGFBP-5 levels in the skeletal muscles of Class II heart failure patients play critical roles in MHC isoform distribution, which switch to more glycolytic properties, evidenced by a significant increase in hybrid isoforms and in particular the MHC IIa/IIx isoforms

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A multicenter, multinational analysis of mitomycin C in refractory metastatic colorectal cancer 48(6):820-6, 2012