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However, the key difference for both model is the Apc status

Component therapy allows only the specific blood components, such as red blood cells, platelets, or plasma, to be transfused rather than the whole blood

Therefore our list is a bit longer, and we have preferred to classify the effect into two groups, where predictable haemolysis means that AHA can be expected in a G6PD-deficient patient, whereas possible haemolysis means that AHA may or may not take place, depending on dosage, other concomitant drugs, co-morbidity and other factors

However, different category does not guarantee safety

This SCFA-mediated reinforcement of intercellular junctions reduces the risk of increased intestinal permeability, commonly referred to as leaky gut, a pathological condition that enables the translocation of luminal antigens and other deleterious molecules into the systemic circulation (170)

Concerning the animal and human studies, the aspects of all of these articles were described thoroughly