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The reviewer JD declared a shared affiliation with the authors MM, ZG, SZ, EI to the handling editor at the time of review

This contradictory observation may be derived from different experimental contexts

More work is needed to fully understand SELENORs function within the brain, though preliminary literature has identified an essential antioxidant function within the hippocampus

doi: 10.1016/j.stemcr.2017.12.007

Muhammad T, Wan Y, Sha Q, et al

The use of growth factors, both in animal models and in clinical trials, has shown promising effects in protecting dopaminergic neurons and astrocytes in damaged regions by the activation of different signaling pathways important in neuronal survival and regeneration
