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10.1038/s41392-021-00701-5 83 ZhangT.ChaboryE.BritanA.GrignardE.PitiotO.SaezF.et al (2008)

In clinical studies, metformin therapy was associated with improved clinical outcomes, including reduced TB severity, and a lower incidence of latent TB infection (LTBI) [118]
Yes, many people find it beneficial to take both, as they support different aspects of health
Superdosing isnt going to turn you into a marathon runner overnight
Payer-specific billing guidelines, particularly for Medicare and Medicaid, must be followed

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