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AHR assessment using the FinePointe RC system (Buxco Research Systems), pulmonary ILC2 and BAL fluid cell analysis, cytokine measurement in BAL supernatant, and lung histological examination were performed according to the established protocols (46, 48, 71, 74)

On the other hand, treatment of rats with ethanol caused a significant increase (3.5-fold) in gastric mucosal MDA concentration as compared to the controls ( P = 0.000) (Figure 7)

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These findings suggest that coated nanoporous membranes are promising systems for localized active donepezil drug delivery for AD-like symptoms modulation in STZ-induced AD model, warranting further validation in other AD paradigms