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[8] Similarly, individuals with thyroid disorders should be aware that ALA might affect thyroid hormone levels

When considering supplements, it's important to consult with a healthcare provider to determine the most effective form based on individual health needs and goals

Under physiological conditions, approximately 40% of the total Mn stored in the body is accumulated in bone tissue, as determined in autopsy studies 21,22

Science, 2006

Planta 133:2125 Foyer CH, Lelandais M, Galap C, Kunert KJ (1991) Effects of elevated cytosolic glutathione reductase activity on the cellular glutathione pool and photosynthesis in leaves under normal and stress conditions

Thus, it could be that GSH-cognition relationships only emerge in cases of more severe cognitive decline, when brain resources (such as antioxidant availability) have substantially declined