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This creates a more balanced immune environment, which supports tissue repair and reduces the risk of chronic inflammation and fibrosis (Bataille & Letenneur, 2020)

18 UC is characterized by ulceration of the intestinal mucosal layer in the rectum and colon, which in turn affects the entire colon, resulting in dysregulation of intestinal immune factors and disruption of the structure and function of the intestinal barrier

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Helenalin, an anti-inflammatory sesquiterpene lactone from Arnica, selectively inhibits transcription factor NF-B

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