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Direct evidence that oxygen-derived free radicals contribute to postischemic myocardial dysfunction in the intact dog

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Caspase-3 activity was quantified in nanomoles of 7-Amino-4-methylcoumarin (the fluorescent product) liberated from acetyl-Asp-Glu-Val-Asp-7-amido-4-methylcoumarin per minute per milliliter of cell lysate, calculated using the formula: Where v = volume of the sample in milliliters, d = dilution factor, and t = reaction time in min

ZZ: Conceptualization, Formal analysis, Methodology, Resources, Writing original draft

Housman, and J
Bcl-2 homology 3 (BH3) mimetics are a class of drugs that antagonise anti-apoptotic BCL-2 family proteins
