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Studies have shown that cuproptosis leads to the release of mitochondrial DNA (mtDNA) into the cytoplasm, activating the cGAS-STING innate immune pathway, which in turn induces IFN production and immunogenic cell death (ICD), recruiting and activating cytotoxic T lymphocytes [105,106]
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Jgou et al., 2000
34%, respectively) and 20 bpm or more (26% vs
Aging and osteoarthritis: the role of chondrocyte senescence and aging changes in the cartilage matrix
