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[DOI] [PubMed] [Google Scholar] Weber-Stadlbauer U, Richetto J, Zwamborn RAJ, Slieker RC, Meyer U (2021) Transgenerational modification of dopaminergic dysfunctions induced by maternal immune activation

Psychosis, mania, aggression or severe high-dopamine behavioral dysregulation

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Moreover, a humanized anti-AXL monoclonal antibody, tilvestamab, blocks GAS6-mediated AXL receptor activation and has been tested in platinum-resistant HGSOC patients (NCT04893551), but no results have been published

One mechanism of this effect is that THC arrests the cells at the G 2 -M cell cycle checkpoint via downregulation of the cyclin-dependent kinase 1 (Cdc2), as suggested by the reduced sensitivity of Cdc2-overexpressing cells to THC (144)

Melasma is influenced by various factors, including UV radiation, inflammation, and hormonal changes, all of which can generate free radicals and lead to oxidative damage in the skin