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Folates, also known as B9 vitamins, serve as donors and acceptors in one-carbon (C1) transfer reactions

- Combination of vitamin C, vitamin E, and milk thistle to suppress glutathione consumption

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Interventions were grouped into therapeutic classes - including oxytocinergic agents, E/I balance therapeutic targets, metabolic drugs, cannabinoids, purine-based interventions and emerging targets - alongside microbiota-directed strategies such as probiotics, prebiotics, and fecal microbiota transplantation

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