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At the same time, reduced IDO activity reduced kynurenine and further weakened peripheral immune tolerance, which played a driving role in the hypothyroidism immune disorder caused by the imbalance of the whole gut microbiota (Clarke et al., 2017)

Only two intermediates, succinate and malate, were detected due to the detection limit of the UHPLC-ESI-MS/MS system

The structural features of the fluorophore indicated the basic mechanism of the fluorescence generation as excited-state intramolecular proton transfer (ESIPT) according to some previous reports (Zhou and Han, 2018)

From this large-scale effort, it was found that residues flanking the serine, threonine, and cysteine involved in thioetherification are less flexible to change due to recognition by enzymes that process the lanthipeptide precursors

Ganley, personal communication)
