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Lancet 378(9789):412419 Parish, C.L

[DOI] [PMC free article] [PubMed] [Google Scholar] 122.Sabari JK, Leonardi GC, Shu CA, Umeton R, Montecalvo J, Ni A, Chen R, Dienstag J, Mrad C, Bergagnini I, et al

39, 40 The consequence of an overall increase in ROS is a reduction in the bioavailability of NO

An evaluation of secukinumab for the treatment of moderate-to-severe hidradenitis suppurativa

10.1126/scisignal.aas8779 16 GulerG

Experimental evidence from human tumor cell lines derived from either colon, breast, melanoma, osteosarcoma and prostate cancers showed increased exosomal release as the pH was changed from 7.4 to 6.5, supporting the notion that acidic TME is associated with increased exosome production and represents a key phenotype of all human cancers [155]
