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68,69 Indeed, the pathogenesis of many diseases without clear protein targets is related to non-coding RNA, which can be used to predict the advantages of ASO in treating diseases

In animal studies, MT has been shown to mitigate oxidative stress, apoptosis, and cardiac dysfunction induced by high glucose and STZ by modulating the AMPK/SIRT1 signaling pathway (Wang et al., 2021)

W., Siu, T

Immunosenescence is associated with dysregulated signaling pathways (e.g., overactivation of the NF-B signaling pathway and downregulation of the melatonin signaling pathway) and abnormal immune cell responses with functional alterations and phenotypic shifts

2019;5:eaaw2238

Malek, City of Hope, United States Updates Copyright 2025 Zhang, Zhang, Ren, Sun, Yang and Wang