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2020;183(3):549-564.[DOI] 105
The FDA recommends using a non-oral contraceptive method or adding a barrier method for 4 weeks after starting treatment and for 4 weeks after each dose increase
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Intestinal inflammation, dysbiosis, or increased permeability can significantly reduce DAO production and allow dietary histamine to enter circulation unchecked
This is why the "just rest it" approach so often fails
