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[16] [18] Healthcare providers should weigh the anticipated benefits against potential risks and consider alternative routes or lower doses when appropriate

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This article is provided strictly for in-vitro laboratory and research purposes

While there is not much doubt that traumatic disc herniation can occur in a degenerated segment, 5 and, although documented in biomechanical in-vitro studies, 39 the existence of an isolated annulus fiber rupture with NP herniation caused by a single traumatic event without (proven) pre-existing DD is still debated in the clinical literature