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In humans, acetylation is a major route of biotransformation for many arylamine and hydrazine drugs, as well as for a number of known carcinogens present in diet, cigarette smoke, car exhaust fumes, and environment in general
Although Alox5 was differentially expressed in the RNA-seq dataset, Slc7a11, Gpx4, and Nrf2 did not meet significance thresholds, likely reflecting differences in assay sensitivity or the limited RNA-seq sample size
Pezzella M
Phelan McDermid syndrome (PMS) and HelsmoortelVan der Aa syndrome (HVDAS) PMS results from the loss of one functional copy of the SHANK3 gene of chromosome 22q13 [337]
