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Here we defined a signature of 59 genes and two metabolites (GSH and NADP) that is robustly associated with NRF2 dependency across an extensive panel of cancer cell lines

This is the bodys way of regulating the amount of glutathione in the system

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doi: 10.1073/pnas.212319799 160 FischerJLMihelcEMPollokKESmithML

C Favreau has been a recipient from a fellowship from PLBio and is currently recipient of a grant from the Institut Carnot OPALE