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In sensitivity analyses, we adjusted for eGFR 27 , which could be a mediator or confounder of the TMAO-ASCVD association given that TMAO is renally cleared and that experimental models show that TMAO damages the kidney, increases cystatin C, and reduces eGFR 28,29

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L-carnitine is an amino acid derivative that plays an important role in the transport of fatty acids to the mitochondria and increases energy production required by sperms for normal functioning

[DOI] [Google Scholar] 83.McNulty H., Jacob R.F., Mason R.P

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Silybin, in particular, is recognised for its ability to support liver enzyme balance and promote the repair of liver tissue, making this supplement especially useful for individuals recovering from liver strain or seeking preventive care