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Following OA induction, the rabbits were randomly divided into four groups with 8 subjects, each receiving a different weekly intra-articular treatment starting four weeks after the first collagenase injection

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If you are able to tolerate them then some anti-inflammatory pain relieve in the form of Ibuprofen, or such like, should help

however, these results were not excluded from corrections for multiple comparisons or the heat map generated with the data

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PMID 32310424