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In areas with iodine deficiency, the prevalence can be as high as 1020% (Hatch-McChesney and Lieberman 2022)

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Although human trials are still insufficient and the survival time of treated mice was not increased, researchers found both histological and functional improvement in the KD-treated ALS animal model, with higher motor neuron counts and less motor function impairment ( 4 Hypothetical functional mechanisms for ketogenic diet therapy During diet-induced glucose deficiency, ketone bodies are generated in the liver and circulated in the bloodstream to metabolically active tissues for processing as energy substrates