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In the four-component Ugi reaction, the five different isocyanide derivatives of 4-hydroxythalidomide, in the presence of tritylamine or methylamine, formaldehyde, and acid-containing derivative of the target ligand (JQ1 derivative) yielded different anti-BRD4 PROTACs 178

232 Interestingly, PTEN degradation also occurs independently of H 2 O 2 , as observed in pancreatic cancer cells with elevated prostaglandin production via 5-LOX and COX-2 overexpression

Meier-Menches S

The silane group could hydrolyze and condensate with the -OH group on the surface of ZnFe 2 O 4 @Pt in the aqueous phase environment, thus anchoring Silane-PEG 2K -COOH on the surface of the nanomaterials

Supplementary Data 3), we detected prominent oxidation of other cysteine residues of both GAPDH and PKM (Fig

A reappraisal of macrophage polarization in glioblastoma: histopathological and immunohistochemical findings and review of the literature