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Lastly, given the increased PPP activity observed in CAR T cells of LTR and the role of this metabolic pathway in maintaining cellular redox balance, we measured the reactive oxygen species levels

Cabrera et al., 1987), and these seminal discoveries have since sparked multiple lines of research to further elucidate the many branches and functions of this signaling pathway

McCracken A, Hooda Z, Carbone G, Hofstetter W, Swisher S, Mehran R, Rajaram R, Rice D, Roth J, Vaporciyan A, Walsh G, Mitchell K, Antonoff MB

thus, it has the ability to decrease blood sugar levels in a glucose-dependent manner by enhancing the secretion of insulin

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