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Rabe von Pappenheim, F
Recently, Chen et al (187) developed a folic acid-decorated, manganese dioxide-coated mesoporous silica nanoparticle to co-deliver fluvastatin sodium (MCT4 inhibitor) and metformin, effectively targeting tumor lactate metabolism by promoting lactate production and inhibiting lactate efflux, thereby exacerbating intracellular acidosis and inducing cancer cell death
Xu, C., Akakuru, O
Gastrointestinal symptoms such as nausea, diarrhea, constipation, abdominal distension, and pain are the most frequent side effects [71,138]
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The B-group of vitamins play key roles in energy metabolism, immunity and DNA repair [27]
