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Nevertheless, interindividual response variability, high cost, and adherence challenges may limit widespread clinical implementation

doi: 10.1001/jama.2016.17441 25 NegroMMarzulloNCasoFCalanni PirelliLDAntonaG

[DOI] [PMC free article] [PubMed] [Google Scholar] 30.Liu J, Killilea DW, Ames BN

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Disclosure The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript