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Description

The rats were given daily injections of tesofensine plus a fixed dose of 5-HTP (31 mg/kg, i.p.) and CB (75 mg/kg, i.p.) for 15 days, following one of six protocols: vehicle (control, n = 6 for each group), 5-HTP/CB (31 and 75 mg/kg), tesofensine1 (1 mg/kg, s.c.), tesofensine2 (2 mg/kg, s.c.), tesofensine1 + 5-HTP/CB, and tesofensine2 + 5-HTP/CB

Ramos-Jimnez A, Hernndez-Torres RP, Hernndez-Ontiveros DA, Ortiz-Ortiz M, Lpez-Fregoso RJ, Martnez-Sanz JM, Rodrguez-Uribe G, Hernndez-Lepe MA

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Anorexigenic signaling through TRH and CRH induces anorexia and thermogenesis

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