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Description
In the MPTP mouse model of PD, GSH depletion resulted in elevated oxidative stress in the midbrain and dysfunction of the Excitatory amino acid carrier 1(EAAC1) transporter (Zeevalk et al., 1998)

Nitric oxide (NO) and asymmetric dimethylarginine (ADMA): Their pathophysiological role and involvement in intracerebral hemorrhage
T.Jr.Smith-WellerT.FranklinG

The response of the PPP, under these conditions, is due to the increased demand for NADPH by cells experiencing increased oxidative stress

Glutathione (GSH, PHR1359), glucose (G7528), glutamine (G8540), sodium pyruvate (S8636), 2-Deoxy-D-glucose (2-DG, D8375), trifluoromethoxy carbonyl cyanide phenylhydrazone (FCCP, C2920), and rotenone (R8875) were from Sigma-Aldrich (USA)
Indefinite survirors among mice treated with mixtures of 2-oxopropanal (NSC-79019) and 2,3-dihydroxypropanal (NSC67934) Cancer Chemother
