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The pivotal human work used oral dosing

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Some synthetic forms do differ slightly from the natural version in structure or form, which can influence how they are absorbed, transported, or used - with a knock-on effect to any health benefits

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In one human study, female participants who applied a topical cream containing all five growth factors daily for four weeks experienced the following: 4 Decreased wrinkles under the eyes by 46% Reduced appearance of crow's feet by 21% Increased skin elasticity by 47% Enhanced skin hydration by 64% (improved by 83% immediately after applying) Accelerate Epidermal Regeneration Epidermal stem cells are responsible for self-renewing the skin's surface