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Description
The generation of mitochondrial NADPH by NADK2-mediated phosphorylation of NAD + is a critically important reaction that is required for mitochondrial fatty acid synthesis, mitochondrial proline synthesis, regulation of redox status, and overall systemic energy homeostasis

Defective mitochondrial biogenesis: a hallmark of the high cardiovascular risk in the metabolic syndrome

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Kolovrat et al., 2020

Obesity has become a global public health problem
By binding to toxins, it facilitates their elimination from the body
