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Annals of Neurology 2003

273 , R1891R1899 (1997)

M.GliiB.RandjeloviP

Psychiatric disorders, including schizophrenia, and mood disorders, such as major depressive disorder (MDD) and bipolar disorder (BD), have been linked to dysregulation in the cholinergic system and dysfunction of cholinergic muscarinic receptors, specifically the M 1 and M 4 receptor for schizophrenia and the M 2 receptor for BD [510]

Research Insights: This is also one of the few areas of nutrition with large-scale clinical trial data behind it

Additionally, rat models are utilized to determine histone deacetylase inhibitors (HDACi) in post injury treatment as a neuroprotectant in acute TBI [6]