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Given the similarity in structure between carnitine and choline, they figured that the same kind of transformation would occur into TMAO

Am J Clin Nutr 2000 Aug;72(2 Suppl):618S-23S Volek JS, Kraemer WJ, Rubin MR, Gomez AL, Ratamess NA, Gaynor P

This effect was independent of IGF-1, a downstream mediator of GH-induced somatic growth, as IGF-1 treatment had minimal impact on the bone and BMAT changes (176, 337)

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( l ) RAD51 foci (n = 3 technical replicates representative from 3 independent experiments in each cell line)

In this shuttle, the CoA group is first exchanged for carnitine in a reaction catalyzed by carnitine palmitoyltransferase 1 (CPT1), forming acylcarnitine