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Synthesis of (((ethane-1,2-diylbis(azanediyl))bis(carbonyl))bis(4,1-phenylene))diboronic acid(EBPBA) 4-Carboxyphenylboronic acid (3.65 g, 22.00 mmol), ethylenediamine dihydrochloride (1.33 g, 10.00 mmol), HATU (11.40 g, 30.00 mmol) and HOAT (4.08 g, 30.00 mmol) were dissolved in DMF (40 mL) under nitrogen atmosphere and ice bath conditions

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Apr 2010;7(4):1342-65

Alarm symptoms: Warning signs to watch out for, as they may indicate serious diseases that require medical attention, include difficulty swallowing, nausea or vomiting that persists or is accompanied by blood, unexplained weight loss, a chronic cough, a sensation of choking, or a lump in the throat

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It was first identified in human plasma and has since become a major subject of interest in regenerative biology, tissue engineering, and extracellular matrix research