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Figure 3 3.5 Transcriptomic profiling and identification of DEGs RNA-Seq was conducted to assess mRNA expression profiles in BAT and to investigate transcriptional alterations across the four groups

However, what about those surprise situations

Effects of tirzepatide vs semaglutide on -cell function, insulin sensitivity, and glucose control during a meal test

Gastrointestinal side effectsincluding nausea, vomiting, and diarrheaare among the most commonly reported adverse reactions with semaglutide
About 56% of participants had type 2 diabetes, and about 73% had obesity

The SELECT safety analysis found breast cancer rates were marginally lower on semaglutide than placebo, and a 2025 meta-analysis of 50 randomised GLP-1 trials found no increased breast cancer risk