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Andersson BS et al
As PHDs are 2-oxoglutarate (2-OG, -ketoglutarate)-dependent dioxygenases, chemical 2-OG analogs can be used for PHD inhibition and HIF- stabilization and can serve as leads for drug discovery targeting the HIF/EPO axis
Additionally, the peptide provides gastroprotective effects and supports neuromuscular function
10.3233/JAD-2009-1073 J
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10.1021/tx050206j 117 MinochaR.ThangavelP.DhankherO
