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Upon activation, JAK2 phosphorylates STAT3, leading to STAT3 dimerization, translocation to the nucleus, and binding to target gene promoters

10.1002/jcla.24345 9

Merrill, Oregon State University) followed by goat-anti-rabbit horseradish peroxidase-conjugated secondary antibody and visualization by chemoluminescence (Pierce PicoWest system) 20
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Glutamate signaling in peripheral tissues

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