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Western blot analysis The tissue homogenates were processed for immunoblotting studies

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Appendix 1 Search strategies Main search EMBASE 1996 to 2007 week 43 Ovid MEDLINE 1996 to October week 3 2007 AMED (Allied and Complementary Medicine) 1985 to October 2007 Repeat search strategies in MEDLINE and EMBASE for high specificity for systematic reviews or RCTs on chondroitin or glucosamine for osteoarthritis