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The clinical picture of cats with LC varies widely and has significant overlap with other forms of hepatobiliary disease in cats, including NC.4, 9 Although some studies describe a predominance of older cats, 3 others describe more younger cats.22, 23 Nonspecific clinical signs, including anorexia, lethargy, vomiting, and weight loss, may be chronic and intermittent.3, 6, 22 Physical examination findings may include icterus, hepatomegaly, or ascites, but none are consistent findings

Vollset SE, Clarke R, Lewington S, Ebbing M, Halsey J, Lonn E, et al

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Brefeldin A (BFA), a ER-to-Golgi transport inhibitor, and monensin, a Golgi-to-PM transport inhibitor, abrogated VRK2 overexpression induced increase in the expression of SLC7A11 at PM level (Fig

Studies consistently find that glutathione exhibits powerful and diverse effects on the immune system, either by stimulating or inhibiting the immune response to regulate levels of inflammation 7

Similarly, doped and polymer-based CQDs, including nitrogen-, copper-, and poly (lactic-co-glycolic acid)-doped systems, have shown improved stability, synergistic fluorescence, theranostic capabilities [91, 182]