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During oxidative phosphorylation, mitochondria produce ATP, and electron leakage during electron transport or NADPH oxidase on the cell membrane leads to the production of superoxide anions
The results of our study demonstrated a marked reduction of HM induced OS with EECGL supplementation, suggesting the role of EECGL in preventing HM induced systemic anomalies either by directly acting as a ROS scavenger or by indirectly modifying the cell signalling system which altered the redox-equilibrium
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doi: 10.1186/1471-2202-13-156
Cancer 1 , 2845 (2020)
