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MIA can even induce transgenerational effects on brain and behavior, modifying dopaminergic activity across multiple generations, possibly through DNA methylation of the dopamine-specific factor nuclear receptor-related 1 protein (Weber-Stadlbauer et al., 2021)

The signs and symptoms of overdose/toxicity due to scopolamine should be carefully distinguished from the occasionally observed syndrome of withdrawal [see Warnings and Precautions (5.6)]

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