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In a randomized trial, objective vitiligo repigmentation obtained with topical catalase/dismutase superoxide (C/DSO) treatment is similar to topical 0.05% betamethasone [102], highlighting the need for better antioxidant medications

focused specifically on measuring putative notochordal and NP cell markers and found expression levels of previously identified novel NP and notochordal markers such as KRT8 , KRT18 , KRT19 , CA12 , FOXA2 , and NOG stayed consistent regardless of donor age or degeneration (Richardson et al., 2017)

However, conflicting results have also been reported

Same principle

Thus, although some of the damage in this experimental model of colitis reflects a direct erosive effect of TNBS and ethanol, their combined administration to rats reflects the in vivo operation of the damaging mechanisms elicited by TNBS, namely GSH depletion and ROS generation, indicating that ethanol facilitates the access of TNBS to the cell interior ensuring TNBS-induced GSH depletion and ROS generation

[1] Subsequently, a 1992 JAMA article led by Guyatt proved instrumental in bringing the concept of evidence-based medicine to the world's attention